Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SOD1 | P00441 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333719 | 0.85 | MEN1 (0.41) | MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30722421 | 0.82 | MAPT (0.78) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL27178667 | 0.81 | KMT2A (0.60) | MAPTKMT2AMEN1HTR1AACHE | |
| SCHEMBL8352689 | 0.80 | MAPT (0.78) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4822865 | 0.80 | MAPT (0.57) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL31334600 | 0.77 | MAPT (0.52) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL2882026 | 0.77 | HTR1A (0.65) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4191910 | 0.77 | SIRT6 (0.72) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL30985146 | 0.76 | MAPT (0.67) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL28901607 | 0.76 | MEN1 (0.66) | MAPTALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |