Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 14/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29919906 | 0.94 | SIGMAR1 (0.45) | SIGMAR1TMEM97 | |
| SCHEMBL22291366 | 0.88 | CRBN (0.54) | — | |
| SCHEMBL29919831 | 0.85 | CRBN (0.47) | SIGMAR1TMEM97 | |
| SCHEMBL27098632 | 0.85 | CRBN (0.54) | SIGMAR1TMEM97 | |
| SCHEMBL29547197 | 0.85 | CRBN (0.54) | SIGMAR1TMEM97 | |
| SCHEMBL22951134 | 0.84 | CRBN (0.47) | — | |
| SCHEMBL29919925 | 0.84 | CRBN (0.47) | — | |
| SCHEMBL29919877 | 0.84 | CRBN (0.54) | SIGMAR1TMEM97 | |
| SCHEMBL23867163 | 0.82 | TMEM97 (0.44) | SIGMAR1TMEM97 | |
| SCHEMBL31333737 | 0.82 | ENPP2 (0.42) | SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590079-B2 | Compounds and uses thereof | FOGHORN THERAPEUTICS INC. (US) | 2026-03-31 | — | — | US | disclosed |
| US-20220289711-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2022-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12590079-B2 | Compounds and uses thereof | PSMB6, PSMC4, PSMB2 | SIGMAR1 1553/4885TMEM97 1396/4885 |
| US-20220289711-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | SIGMAR1 2852/4885TMEM97 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.