Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334454 | 0.87 | DRD2 (0.49) | DRD2ALDH1A1ADAM10ERBB2CCNT1 | |
| SCHEMBL31334286 | 0.81 | ACHE (0.38) | DRD2DRD3WDR5ALDH1A1 | |
| SCHEMBL27224905 | 0.81 | DRD2 (0.59) | DRD2DRD3HTR1AHTR2AALDH1A1 | |
| SCHEMBL31333302 | 0.80 | DRD2 (0.42) | DRD2ALDH1A1CCNT1CDK9 | |
| SCHEMBL31333911 | 0.79 | SIGMAR1 (0.38) | DRD2WDR5HTR2AALDH1A1 | |
| SCHEMBL31334849 | 0.78 | DRD2 (0.54) | DRD2DRD3ALDH1A1KCNA3 | |
| SCHEMBL31333521 | 0.77 | SIGMAR1 (0.44) | WDR5HTR2AALDH1A1ADAM10ERBB2 | |
| SCHEMBL29535433 | 0.76 | PDK4 (0.51) | ALDH1A1JAK1CCNT1CDK9 | |
| SCHEMBL10036179 | 0.76 | PDK4 (0.51) | ALDH1A1JAK1CCNT1CDK9 | |
| SCHEMBL30915181 | 0.75 | DRD2 (0.54) | DRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |