SCHEMBL31334006

SCHEMBL31334006

O=C1CCC(N2Cc3cc(C4CCN(C5CCCN(CC(=O)N6CCC(Nc7ncc(Cl)c(-c8cccc(-c9ccc(F)cc9)c8)n7)CC6)C5)CC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 11/20 0.45
IKZF1 Q13422 2/20 0.44
IKZF2 Q9UKS7 5/20 0.43
DDB1 Q16531 2/20 0.43
CRBN Q96SW2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333416 0.89 IKZF1 (0.52) MAPK1IKZF1IKZF2
SCHEMBL31334649 0.87 CRBN (0.42) MAPK1CRBN
SCHEMBL31333570 0.86 IKZF1 (0.49) MAPK1IKZF1IKZF2
SCHEMBL31333319 0.86 MAPK1 (0.40) MAPK1CRBN
SCHEMBL31334220 0.86 IKZF1 (0.50) MAPK1IKZF1IKZF2
SCHEMBL31334864 0.85 IKZF1 (0.52) MAPK1IKZF1IKZF2
SCHEMBL31333738 0.82 IKZF1 (0.51) MAPK1IKZF1IKZF2
SCHEMBL31333415 0.82 IKZF1 (0.53) MAPK1IKZF1IKZF2
SCHEMBL31333740 0.81 MAPK1 (0.44) MAPK1IKZF1
SCHEMBL31333656 0.79 IKZF1 (0.49) MAPK1IKZF1IKZF2DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed