Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | NEK1 | Q96PY6 | 4/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SDHB | P21912 | 1/20 | 0.43 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379140 | 0.84 | MAP2K4 (0.45) | ERN1GABRA5L3MBTL1 | |
| SCHEMBL22097954 | 0.81 | NPC1 (0.41) | NPC1RAB9AL3MBTL1ABL1CNR1 | |
| SCHEMBL14892283 | 0.80 | CDK8 (0.61) | CDK8RAB9AERN1GABRG2GABRB3 | |
| SCHEMBL17634951 | 0.78 | L3MBTL1 (0.56) | L3MBTL1BTK | |
| SCHEMBL12519774 | 0.78 | MAPK1 (0.54) | RAB9AABL1BCRSRC | |
| SCHEMBL15577299 | 0.78 | CLK4 (0.46) | NPC1RAB9A | |
| SCHEMBL24054111 | 0.78 | KDR (0.38) | CDK8 | |
| SCHEMBL38656270 | 0.77 | CDK8 (0.58) | CDK8NPC1RAB9AERN1GABRG2 | |
| SCHEMBL27928801 | 0.76 | ALDH1A1 (0.51) | CDK8NPC1RAB9AERN1GABRG2 | |
| SCHEMBL15577176 | 0.75 | BTK (0.46) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |