Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.41 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10059908 | 0.74 | HRH3 (0.49) | KDM4ELMNAALDH1A1MGLLCYP1A2 | |
| SCHEMBL16474659 | 0.73 | KDM4E (0.41) | KDM4ELMNAALDH1A1MGLLCYP1A2 | |
| SCHEMBL147877 | 0.73 | ALDH1A1 (0.67) | KDM4ELMNAALDH1A1MGLLCYP1A2 | |
| SCHEMBL2466555 | 0.72 | TYR (0.50) | KDM4ELMNAALDH1A1MGLLCYP1A2 | |
| SCHEMBL2459006 | 0.72 | KDM4E (0.51) | KDM4ELMNAALDH1A1HPGDMEN1 | |
| SCHEMBL142716 | 0.71 | NPC1 (0.46) | KDM4ELMNAALDH1A1MGLLCYP1A2 | |
| SCHEMBL16474401 | 0.71 | HSD17B10 (0.43) | KDM4ELMNAALDH1A1CYP1A2HPGD | |
| SCHEMBL2462606 | 0.70 | ALDH1A1 (0.44) | KDM4ELMNAALDH1A1MGLLCYP1A2 | |
| SCHEMBL21979751 | 0.70 | ORAI1 (0.68) | ORAI1ORAI2ORAI3TRPV6KDM4E | |
| SCHEMBL5508 | 0.70 | ORAI1 (0.68) | ORAI1ORAI2ORAI3TRPV6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |