SCHEMBL5508

SCHEMBL5508

OB(O)c1ccc(F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ORAI1 Q96D31 1/20 0.68
ORAI2 Q96SN7 1/20 0.68
ORAI3 Q9BRQ5 1/20 0.68
TRPV6 Q9H1D0 1/20 0.68
ENPP2 Q13822 5/20 0.55
CA2 P00918 5/20 0.52
CA1 P00915 4/20 0.52
LPL P06858 2/20 0.52
LIPG Q9Y5X9 2/20 0.52
TSHR P16473 1/20 0.52
MGLL Q99685 2/20 0.52
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
KDM4E B2RXH2 1/20 0.46
F11 P03951 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21979751 1.00 ORAI1 (0.68) ORAI1ORAI2ORAI3TRPV6ENPP2
SCHEMBL18839425 0.97 ORAI1 (0.65) ORAI1ORAI2ORAI3TRPV6ENPP2
SCHEMBL2551749 0.92 CA2 (0.61) ORAI1ORAI2ORAI3TRPV6ENPP2
Phenylboronic Acid SCHEMBL28610016 0.89 ENPP2 (0.70) ORAI1ORAI2ORAI3TRPV6ENPP2
SCHEMBL13806989 0.87 ORAI1 (0.54) ORAI1ORAI2ORAI3TRPV6ENPP2
SCHEMBL257871 0.85 CA2 (0.65) ORAI1ORAI2ORAI3TRPV6ENPP2
SCHEMBL22609233 0.85 ORAI1 (0.52) ORAI1ORAI2ORAI3TRPV6ENPP2
Bicarbonate SCHEMBL28930263 0.85 ORAI1 (0.52) ORAI1ORAI2ORAI3TRPV6ENPP2
SCHEMBL31514900 0.83 LTA4H (0.55) ORAI1ORAI2ORAI3TRPV6CA2
SCHEMBL204921 0.83 ENPP2 (0.73) ENPP2CA2CA1LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14451 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122051374-A Battery monomer, preparation method and application thereof 浙江晶科储能有限公司 2026-05-15 CN claimed
EP-4720728-A1 COATED SILICONE HYDROGEL CONTACT LENSES AND METHOD FOR MAKING THE SAME Alcon Inc. (CH) 2026-04-08 EP claimed
US-12528777-B2 Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2026-01-20 US claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250177537-A1 AN ANTIBIOTIC, METHOD OF PREPARATION AND METHOD OF TREATMENT THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2025-06-05 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-116217764-B Triazine polymer and preparation method and application thereof 南京邮电大学 2025-05-27 CN claimed
CN-119799320-A Organic narrow-band afterglow material based on halation benzene derivative and preparation and application methods thereof 中国科学院上海有机化学研究所 2025-04-11 CN claimed
CN-119591560-A Synthesis method of thifluzamide 湖南速博生物技术有限公司 2025-03-11 CN claimed
CN-117603044-B Method for depolymerizing and upgrading polyester into carboxylate and borate by using ionic liquid to catalyze 浙江大学 2025-03-07 CN claimed
EP-1107982-B1 REVERSIBLE BORON COMPLEXES OF 1,2-(CIS)-DIOL CYCLIC PEPTIDES LILLY CO ELI (US) 2004-05-19 EP claimed
US-20040053889-A1 Pharmaceutical use of boronic acids and esters thereof NOVO NORDISK A/S (DK) 2004-03-18 US claimed
WO-2003105860-A1 PHARMACEUTICAL USE OF BORONIC ACIDS AND ESTERS THEREOF NOVO NORDISK A/S (DK) 2003-12-24 WO claimed
US-20030211138-A1 Temperature control system for cutaneous photodynamic therapy SPECTRA SYSTEMS CORPORATION 2003-11-13 US claimed
WO-2003070315-A2 TEMPERATURE CONTROL SYSTEM FOR CUTANEOUS PHOTODYNAMIC THERAPY SPECTRA SYSTEMS CORPORATION (US) 2003-08-28 WO claimed
US-6590100-B2 Reacting an aromatic compound bearing a leaving group and an arylboronic acid and/or its derivatives in the presence of a base and an effective amount of a nickel catalyst RHODIA CHIMIE (FR) 2003-07-08 US claimed
US-20020173652-A1 Process for preparing a polyaromatic compound SHASUN PHARMA SOLUTIONS, INC. 2002-11-21 US claimed
EP-1064286-A1 SYNTHESIS OF ARYL BORONIC ACIDS BOULDER SCIENTIFIC COMPANY (US) 2001-01-03 EP claimed
WO-1999064428-A1 SYNTHESIS OF ARYL BORONIC ACIDS BOULDER SCIENTIFIC COMPANY (US) 1999-12-16 WO claimed
WO-1995005081-A1 BIOCIDAL COMPOSITIONS CONTAINING ORGANOBORON COMPOUNDS U.S. BORAX INC. (US) 1995-02-23 WO claimed