Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.68 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.68 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.68 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.68 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | LPL | P06858 | 2/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508 | 1.00 | ORAI1 (0.68) | ORAI1ORAI2ORAI3TRPV6ENPP2 | |
| SCHEMBL18839425 | 0.97 | ORAI1 (0.65) | ORAI1ORAI2ORAI3TRPV6ENPP2 | |
| SCHEMBL2551749 | 0.92 | CA2 (0.61) | ORAI1ORAI2ORAI3TRPV6ENPP2 | |
| Phenylboronic Acid SCHEMBL28610016 | 0.89 | ENPP2 (0.70) | ORAI1ORAI2ORAI3TRPV6ENPP2 | |
| SCHEMBL13806989 | 0.87 | ORAI1 (0.54) | ORAI1ORAI2ORAI3TRPV6ENPP2 | |
| SCHEMBL257871 | 0.85 | CA2 (0.65) | ORAI1ORAI2ORAI3TRPV6ENPP2 | |
| SCHEMBL22609233 | 0.85 | ORAI1 (0.52) | ORAI1ORAI2ORAI3TRPV6ENPP2 | |
| Bicarbonate SCHEMBL28930263 | 0.85 | ORAI1 (0.52) | ORAI1ORAI2ORAI3TRPV6ENPP2 | |
| SCHEMBL31514900 | 0.83 | LTA4H (0.55) | ORAI1ORAI2ORAI3TRPV6CA2 | |
| SCHEMBL204921 | 0.83 | ENPP2 (0.73) | ENPP2CA2CA1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891393-B2 | Functionalized heterocycles as antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2024-02-06 | — | — | US | disclosed |
| US-20230075366-A1 | FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS | ENANTA PHARM INC (US) | 2023-03-09 | — | — | US | disclosed |
| US-11198693-B2 | Functionalized heterocycles as antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2021-12-14 | — | — | US | disclosed |
| EP-3883570-A1 | FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS | Enanta Pharmaceuticals, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| US-20200165249-A1 | FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891393-B2 | Functionalized heterocycles as antiviral agents | HCCS, HAVCR2, HDGF | ORAI1 3981/4885ORAI2 2761/4885ORAI3 2407/4885 |
| US-20230075366-A1 | FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS | HCCS, HAVCR2, HDGF | ORAI1 3981/4885ORAI2 2761/4885ORAI3 2407/4885 |
| US-11198693-B2 | Functionalized heterocycles as antiviral agents | HCCS, HAVCR2, HDGF | ORAI1 3981/4885ORAI2 2761/4885ORAI3 2407/4885 |
| US-20200165249-A1 | FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS | HCCS, HAVCR2, HDGF | ORAI1 3981/4885ORAI2 2761/4885ORAI3 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.