Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16474401 | 0.85 | HSD17B10 (0.43) | KDM4ELMNACES2CES1KMT2A | |
| SCHEMBL24849954 | 0.85 | BCL2L1 (0.39) | KDM4ELMNABCL2L1BADHTR7 | |
| SCHEMBL146048 | 0.84 | KDM4E (0.56) | KDM4ELMNACES2CES1DDAH1 | |
| SCHEMBL16672361 | 0.83 | SRD5A2 (0.54) | CES2CES1KMT2AMEN1HPGD | |
| SCHEMBL4246208 | 0.83 | ALDH1A1 (0.56) | KDM4ELMNACES2CES1DDAH1 | |
| SCHEMBL11896214 | 0.83 | ALOX15 (0.53) | KDM4ECES2CES1DDAH1KMT2A | |
| SCHEMBL16672330 | 0.81 | L3MBTL1 (0.53) | KDM4ECES2CES1KMT2AMEN1 | |
| SCHEMBL2459873 | 0.81 | KMT2A (0.52) | KDM4ELMNAKMT2AMEN1MAPT | |
| SCHEMBL12311154 | 0.79 | CA1 (0.58) | KDM4ECES2CES1KMT2AMEN1 | |
| SCHEMBL11896441 | 0.79 | NPC1 (0.49) | KDM4EKMT2AMEN1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002346-A1 | NEW COMPOUNDS AND METHODS | BenevolentAl Bio Limited (GB) | 2023-01-05 | — | — | US | disclosed |
| US-20230002346-A1 | NEW COMPOUNDS AND METHODS | BenevolentAl Bio Limited (GB) | 2023-01-05 | — | — | US | disclosed |
| EP-3060549-B1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAE WOONG PHARMA (KR) | 2019-02-13 | — | — | EP | disclosed |
| CN-105745193-B | Antimycotic oxo-dihydro pyridine carbohydrazide derivative | 株式会社大熊制药 | 2017-12-01 | — | — | CN | disclosed |
| US-9617216-B2 | Antifungal oxodihydropyridinecarbohydrazide derivative | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2017-04-11 | — | — | US | disclosed |
| US-20160304460-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2016-10-20 | — | — | US | disclosed |
| EP-3060549-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | Daewoong Pharmaceutical Co., Ltd. (KR) | 2016-08-31 | — | — | EP | disclosed |
| CN-105745193-A | Novel antifungal oxodihydropyridinecarbohydrazide derivative | 株式会社大熊制药 | 2016-07-06 | — | — | CN | disclosed |
| WO-2015060613-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-30 | — | — | WO | disclosed |
| US-8791147-B2 | Calcium receptor modulating agents | AMGEN INC. (US) | 2014-07-29 | — | — | US | disclosed |
| US-8791147-B2 | Calcium receptor modulating agents | AMGEN INC. (US) | 2014-07-29 | — | — | US | disclosed |
| US-8791147-B2 | Calcium receptor modulating agents | AMGEN INC. (US) | 2014-07-29 | — | — | US | disclosed |
| US-20110230517-A1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC. | 2011-09-22 | — | — | US | disclosed |
| US-20110230517-A1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC. | 2011-09-22 | — | — | US | disclosed |
| US-20110230517-A1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC. | 2011-09-22 | — | — | US | disclosed |
| WO-2010042642-A1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC. (US) | 2010-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002346-A1 | NEW COMPOUNDS AND METHODS | ABL2, ABL1, ALK | KDM4E 3546/4885LMNA 1857/4885BCL2L1 1373/4885 |
| US-20160304460-A1 | NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE | PITHD1, HPD, QDPR | KDM4E 841/4885LMNA 4833/4885BCL2L1 2059/4885 |
| US-20110230517-A1 | CALCIUM RECEPTOR MODULATING AGENTS | CASR, CALCR, CNR1 | KDM4E 4037/4885LMNA 3106/4885BCL2L1 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.