Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.44 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.40 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 6/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334189 | 1.00 | SYK (0.44) | SYKMAPK3MAPK6CDK2CCNA2 | |
| SCHEMBL31333611 | 0.92 | SYK (0.41) | SYKMAPK3CDK2CCNA2CCNA1 | |
| SCHEMBL31333557 | 0.89 | CDK9 (0.44) | SYKCDK2MAPK14PCSK9MAPK8 | |
| SCHEMBL31334407 | 0.88 | MAPK8 (0.42) | SYKCDK2CDK1CDK4CCND1 | |
| SCHEMBL31334485 | 0.87 | MAPK1 (0.43) | SYKCDK2CDK1CDK4CCND1 | |
| SCHEMBL31333622 | 0.86 | SYK (0.43) | SYKMAPK3MAPK6CDK2CCNA2 | |
| SCHEMBL31334709 | 0.84 | SYK (0.48) | SYKMAPK3MAPK6CDK2CCNA2 | |
| SCHEMBL31334896 | 0.84 | SYK (0.48) | SYKMAPK3MAPK6CDK2CCNA2 | |
| SCHEMBL31334371 | 0.83 | SYK (0.46) | SYKMAPK1MAPK14MAPK8MAPK9 | |
| SCHEMBL31334634 | 0.82 | CDK2 (0.39) | SYKMAPK3MAPK6CDK2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |