Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 8/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | CCND1 | P24385 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334371 | 0.91 | SYK (0.46) | MAPK1SYKMAPK8MAPK9MAPK10 | |
| SCHEMBL31333611 | 0.88 | SYK (0.41) | MAPK1SYKMAPK8MAPK9MAPK10 | |
| SCHEMBL31334181 | 0.87 | SYK (0.44) | MAPK1SYKMAPK8MAPK9MAPK10 | |
| SCHEMBL31334189 | 0.87 | SYK (0.44) | MAPK1SYKMAPK8MAPK9MAPK10 | |
| SCHEMBL31334407 | 0.85 | MAPK8 (0.42) | MAPK1SYKMAPK8MAPK9MAPK10 | |
| SCHEMBL31333557 | 0.83 | CDK9 (0.44) | SYKMAPK8MAPK9MAPK10MAPK14 | |
| SCHEMBL31333753 | 0.83 | MAPK1 (0.46) | MAPK1MAPK8MAPK9MAPK10MAPK14 | |
| SCHEMBL31334239 | 0.83 | MAPK1 (0.46) | MAPK1MAPK8MAPK9MAPK10MAPK14 | |
| SCHEMBL31334036 | 0.82 | MAPK1 (0.43) | MAPK1MAPK10CDK1CDK4CCND1 | |
| SCHEMBL31334380 | 0.79 | MAPK1 (0.41) | MAPK1SYKMAPK8MAPK9MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |