Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334485 | 0.91 | MAPK1 (0.43) | SYKMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL31334407 | 0.88 | MAPK8 (0.42) | SYKMAPK1CKS1BSKP1SKP2 | |
| SCHEMBL31334297 | 0.88 | MAPK1 (0.47) | SYKMAPK1CKS1BSKP1SKP2 | |
| SCHEMBL31333648 | 0.86 | MAPK1 (0.48) | SYKMAPK1CKS1BSKP1SKP2 | |
| SCHEMBL31333611 | 0.84 | SYK (0.41) | SYKMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL31333937 | 0.83 | CKS1B (0.42) | SYKMAPK1CKS1BSKP1SKP2 | |
| SCHEMBL31334189 | 0.83 | SYK (0.44) | SYKMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL31334181 | 0.83 | SYK (0.44) | SYKMAPK1MAPK8MAPK9MAPK10 | |
| SCHEMBL31333557 | 0.83 | CDK9 (0.44) | SYKMAPK8MAPK9MAPK10MERTK | |
| SCHEMBL31334574 | 0.83 | MAPK1 (0.46) | MAPK1CKS1BSKP1SKP2MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |