Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 8/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 7/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 7/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333611 | 0.89 | SYK (0.41) | MAPK8MAPK9MAPK10CDK2CCNE1 | |
| SCHEMBL31334371 | 0.88 | SYK (0.46) | MAPK8MAPK9MAPK10SYKMAPK14 | |
| SCHEMBL31334189 | 0.88 | SYK (0.44) | MAPK8MAPK9MAPK10CDK2SYK | |
| SCHEMBL31334181 | 0.88 | SYK (0.44) | MAPK8MAPK9MAPK10CDK2SYK | |
| SCHEMBL31333557 | 0.87 | CDK9 (0.44) | MAPK8MAPK9MAPK10CDK2CCNE1 | |
| SCHEMBL31333485 | 0.86 | MAPK8 (0.45) | MAPK8MAPK9MAPK10CDK2CYP2C9 | |
| SCHEMBL31334485 | 0.85 | MAPK1 (0.43) | MAPK8MAPK9MAPK10CDK2SYK | |
| SCHEMBL31334364 | 0.84 | SYK (0.44) | MAPK8MAPK9MAPK10CDK2CYP2C9 | |
| SCHEMBL31334008 | 0.82 | CDK2 (0.41) | MAPK8MAPK9MAPK10CDK2CYP2C9 | |
| SCHEMBL31334585 | 0.81 | MAP4K1 (0.42) | MAPK8MAPK9MAPK10CDK2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |