Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 14/20 | 0.44 |
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | JUN | P05412 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334939 | 1.00 | MAPK1 (0.44) | MAPK1SYKJUNCDK2MAPK8 | |
| SCHEMBL31334819 | 0.93 | SYK (0.42) | MAPK1SYKPCSK9 | |
| SCHEMBL31333721 | 0.88 | MAPK1 (0.45) | MAPK1SYKPCSK9 | |
| SCHEMBL31335065 | 0.88 | MAPK1 (0.45) | MAPK1SYKPCSK9 | |
| SCHEMBL31334357 | 0.86 | SYK (0.46) | MAPK1SYKMAPK8MAPK10PCSK9 | |
| SCHEMBL31334573 | 0.84 | MAPK1 (0.49) | MAPK1SYKJUNCDK2MAPK8 | |
| SCHEMBL31333940 | 0.84 | MAPK1 (0.48) | MAPK1SYK | |
| SCHEMBL31333360 | 0.83 | MAPK3 (0.48) | MAPK1SYKPCSK9 | |
| SCHEMBL31334367 | 0.83 | MAPK1 (0.49) | MAPK1JUNCDK2MAPK8MAPK9 | |
| SCHEMBL31334882 | 0.83 | SYK (0.43) | MAPK1SYKMAPK8PCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |