Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25080825 | 0.79 | DAO (0.39) | CA12CA1CA2CA4CA9 | |
| SCHEMBL31335132 | 0.77 | ENPP2 (0.39) | CA12CA1CA2CA4CA9 | |
| SCHEMBL3886551 | 0.75 | PTGS2 (0.39) | DAOTSHRPTGS2PRSS1PRSS2 | |
| SCHEMBL5178079 | 0.74 | CA12 (0.53) | CA12CA1CA2CA4CA9 | |
| SCHEMBL10959400 | 0.74 | CA12 (0.53) | CA12CA1CA2CA4CA9 | |
| SCHEMBL726899 | 0.73 | ALDH1A1 (0.52) | CA12CA1CA2CA4CA9 | |
| SCHEMBL10743672 | 0.71 | DAO (0.42) | CA12CA1CA2CA4CA9 | |
| SCHEMBL9712031 | 0.71 | CA2 (0.52) | CA12CA1CA2CA4CA9 | |
| SCHEMBL708720 | 0.71 | SLC6A4 (0.53) | CA12CA1CA2CA4CA9 | |
| SCHEMBL3694910 | 0.70 | TSHR (0.43) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119278034-A | Selective histone deacetylase 8 (HDAC 8) degradants and methods of use thereof | 丹娜-法伯癌症研究院 | 2025-01-07 | — | — | CN | disclosed |