Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 6/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 6/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 6/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 6/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 6/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 6/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25156289 | 0.84 | NOTUM (0.44) | NOTUMPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL29638857 | 0.78 | SRC (0.48) | MCL1HSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL435044 | 0.78 | SRC (0.48) | MCL1HSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL1885488 | 0.77 | F7 (0.55) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL18088275 | 0.77 | KDM4E (0.54) | CSNK2A1HSD17B10KDM4EGAAHPGD | |
| SCHEMBL13506440 | 0.76 | F7 (0.53) | NOTUMPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL15730605 | 0.75 | ATM (0.43) | HSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL9442095 | 0.73 | GPR35 (0.69) | F7F3HSD17B10KDM4EHPGD | |
| SCHEMBL12657284 | 0.73 | ATM (0.54) | NOTUMHSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL28706306 | 0.72 | F7 (0.58) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |