SCHEMBL1885488

SCHEMBL1885488

O=C(O)c1c[nH]c2cc(O)c(O)cc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.55
F3 P13726 1/20 0.55
PRKAB2 O43741 12/20 0.50
PRKAG1 P54619 12/20 0.50
PRKAA2 P54646 12/20 0.50
PRKAA1 Q13131 12/20 0.50
PRKAG3 Q9UGI9 12/20 0.50
PRKAG2 Q9UGJ0 12/20 0.50
PRKAB1 Q9Y478 12/20 0.50
GPR35 Q9HC97 1/20 0.46
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP1A2 P05177 1/20 0.45
HPGD P15428 1/20 0.45
ALOX12 P18054 1/20 0.45
KMT2A Q03164 1/20 0.45
KDM4E B2RXH2 1/20 0.45
SRC P12931 1/20 0.43
PRKACA P17612 1/20 0.43
PRKACG P22612 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9319718 0.89 KDM4E (0.59) F7F3MEN1ALDH1A1CYP1A2
SCHEMBL17417592 0.85 CYP2C19 (0.52) F7F3PRKAB2PRKAG1PRKAA2
SCHEMBL28706306 0.83 F7 (0.58) F7F3PRKAB2PRKAG1PRKAA2
SCHEMBL17429453 0.78 PRKAB2 (0.59) F7F3PRKAB2PRKAG1PRKAA2
SCHEMBL30416918 0.78 PRKAB2 (0.59) F7F3PRKAB2PRKAG1PRKAA2
SCHEMBL23612266 0.78 PRKAG1 (0.66) F7F3PRKAB2PRKAG1PRKAA2
SCHEMBL9455846 0.78 KDM4E (0.58) F7F3GPR35MEN1ALDH1A1
SCHEMBL13506440 0.78 F7 (0.53) F7F3PRKAB2PRKAG1PRKAA2
SCHEMBL31335635 0.77 CSNK2A1 (0.43) F7F3PRKAB2PRKAG1PRKAA2
SCHEMBL1081795 0.76 F7 (0.66) F7F3ALDH1A1CYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7270685-B2 Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye L'OREAL (FR) 2007-09-18 US claimed
US-7077871-B2 Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye L'OREAL (FR) 2006-07-18 US claimed
US-20060112501-A1 Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye L'OREAL (FR) 2006-06-01 US claimed
US-20040040097-A1 Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye L'OREAL (FR) 2004-03-04 US claimed
US-20260043059-A1 PRODUCTION OF COLOURANTS IN ENGINEERED BIOLOGICAL SYSTEMS AND METHODS THEREON LITE 1 MICROBIAL COLOUR LTD (CA) 2026-02-12 US disclosed
CN-115997921-A Use of assai for improving skin conditions 黑龙江飞鹤乳业有限公司 2023-04-25 CN disclosed
CN-104894005-B The lactic acid bacteria BL21 and preparation method and application of a kind of high-yield extracellular polysaccharide 江苏紫石微康生物科技有限公司 2018-05-22 CN disclosed
EP-1820491-B1 PROCESS FOR PREPARING A HAIR DYE COMPOSITION KAO CORP (JP) 2018-01-24 EP disclosed
EP-3067041-A1 METHOD FOR DYEING KERATIN FIBERS, KERATIN FIBER DYE Shisei Chemical Co., Ltd. (JP) 2016-09-14 EP disclosed
CN-101914585-B Melanin precursor producing method KAO CORP 2012-06-13 CN disclosed
CN-101558748-B Method for breeding large Sepiella maindroni ink sacs UNIV ZHEJIANG OCEAN 2011-11-16 CN disclosed
US-7939307-B2 Deletion mutant of multi-copper oxidase and its use in dyeing NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) 2011-05-10 US disclosed
US-20090178209-A1 Hair Dye Composition KAO CORPORATION 2009-07-16 US disclosed
EP-1961812-A1 IMPROVED MULTI-COPPER OXIDASE CueO WITH DYEABILITY National University Corporation Kanazawa University (JP) 2008-08-27 EP disclosed
US-7270685-B2 Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye L'OREAL (FR) 2007-09-18 US disclosed
EP-1820491-A1 HAIR DYE COMPOSITION Kao Corporation (JP) 2007-08-22 EP disclosed
US-7077871-B2 Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye L'OREAL (FR) 2006-07-18 US disclosed
US-20060112501-A1 Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye L'OREAL (FR) 2006-06-01 US disclosed
US-20040040097-A1 Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye L'OREAL (FR) 2004-03-04 US disclosed
WO-2002002066-A1 NAPHTHOMELANINS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS THEREOF GHISALBERTI CARLO (BR) 2002-01-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040040097-A1 Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye KRT18, HMOX2, HAO2 F7 2256/4885F3 2985/4885PRKAB2 2368/4885
US-20260043059-A1 PRODUCTION OF COLOURANTS IN ENGINEERED BIOLOGICAL SYSTEMS AND METHODS THEREON TYR, TH, TDO2 F7 2748/4885F3 1453/4885PRKAB2 2746/4885
US-20060112501-A1 Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye KRT18, ALPP, ALPI F7 1698/4885F3 3546/4885PRKAB2 2135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.