Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 4/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30035471 | 0.81 | ATAD2 (0.41) | LCKFYNPGRRXRAHSD17B10 | |
| SCHEMBL23577902 | 0.81 | ATAD2 (0.41) | LCKFYNPGRRXRAHSD17B10 | |
| SCHEMBL31335591 | 0.80 | ATAD2 (0.42) | ALDH1A1KDM4EHPGDPGRRXRA | |
| SCHEMBL30642295 | 0.80 | GRIN2D (0.45) | PGRATAD2PDK2PDK4MAP3K11 | |
| SCHEMBL31335589 | 0.80 | ATAD2 (0.42) | ALDH1A1KDM4EHPGDPGRRXRA | |
| SCHEMBL26640169 | 0.80 | GRIN2D (0.45) | PGRATAD2PDK2PDK4MAP3K11 | |
| SCHEMBL30459958 | 0.78 | PGR (0.43) | KDM4EPGRRXRAATAD2PDK2 | |
| SCHEMBL25156363 | 0.76 | MAPK14 (0.46) | KDM4EHPGDPGRRXRAHSD17B10 | |
| SCHEMBL23590768 | 0.75 | ATAD2 (0.39) | KDM4EPGRATAD2PDK2PDK4 | |
| SCHEMBL30183994 | 0.75 | ATAD2 (0.39) | KDM4EPGRATAD2PDK2PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |