Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TCF4 | P15884 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27247073 | 0.86 | KDM4E (0.44) | KDM4ELMNATSHRL3MBTL1FFAR4 | |
| SCHEMBL30920412 | 0.80 | MTNR1B (0.41) | KDM4ELMNATSHRL3MBTL1HSD17B10 | |
| SCHEMBL18584655 | 0.76 | FFAR4 (0.52) | KDM4ELMNATSHRL3MBTL1FFAR4 | |
| SCHEMBL31336002 | 0.75 | KDM4E (0.48) | KDM4ELMNATSHRL3MBTL1HSD17B10 | |
| SCHEMBL27247273 | 0.75 | MTNR1B (0.45) | KDM4ELMNATSHRL3MBTL1HSD17B10 | |
| SCHEMBL10002626 | 0.73 | NOD1 (0.61) | KDM4ELMNATSHRL3MBTL1HSD17B10 | |
| SCHEMBL30920598 | 0.72 | MTNR1B (0.42) | KDM4ELMNATSHRL3MBTL1MAPK1 | |
| SCHEMBL30920116 | 0.72 | NOD2 (0.47) | KDM4ELMNATSHRL3MBTL1HSD17B10 | |
| SCHEMBL27247710 | 0.72 | NOD2 (0.47) | KDM4ELMNATSHRL3MBTL1HSD17B10 | |
| SCHEMBL16382679 | 0.71 | LMNA (0.49) | KDM4ELMNATSHRL3MBTL1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |