Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335950 | 0.83 | DDB1 (0.47) | ABHD6DDB1CRBNNAMPTMAPK1 | |
| SCHEMBL31013975 | 0.81 | DDB1 (0.46) | ABHD6DDB1CRBNNAMPTMAPK1 | |
| SCHEMBL31335935 | 0.81 | DDB1 (0.49) | ABHD6DDB1CRBNNAMPTMAPK1 | |
| SCHEMBL30368301 | 0.80 | DDB1 (0.48) | ABHD6DDB1CRBNUSP2SMN1; SMN2 | |
| SCHEMBL25669124 | 0.80 | DDB1 (0.48) | ABHD6DDB1CRBNUSP2SMN1; SMN2 | |
| SCHEMBL2335199 | 0.80 | ABHD6 (0.72) | ABHD6LMNACD274THRBNAMPT | |
| SCHEMBL17686920 | 0.79 | DDB1 (0.47) | ABHD6DDB1CRBNNAMPTMAPK1 | |
| SCHEMBL31335629 | 0.78 | NAMPT (0.45) | DDB1CRBNNAMPTMAPK1 | |
| SCHEMBL31336063 | 0.77 | DDB1 (0.43) | DDB1CRBNSMN1; SMN2NAMPTMAPK1 | |
| SCHEMBL31335890 | 0.77 | ACHE (0.48) | LMNADDB1CRBNNAMPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |