Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31335944 | 0.90 | HTT (0.48) | DDB1CRBNNAMPTMAPK1GPR119 | |
| SCHEMBL31335950 | 0.84 | DDB1 (0.47) | DDB1CRBNNAMPTMAPK1GLS | |
| SCHEMBL31013975 | 0.82 | DDB1 (0.46) | DDB1CRBNNAMPTMAPK1GLS | |
| SCHEMBL31335935 | 0.81 | DDB1 (0.49) | DDB1CRBNNAMPTMAPK1GLS | |
| SCHEMBL31335890 | 0.80 | ACHE (0.48) | DDB1CRBNNAMPTMAPK1GPR119 | |
| SCHEMBL17686920 | 0.79 | DDB1 (0.47) | DDB1CRBNNAMPTMAPK1GLS | |
| SCHEMBL31013972 | 0.78 | DDB1 (0.52) | DDB1CRBNNAMPTMAPK1GLS | |
| SCHEMBL15893731 | 0.78 | DDB1 (0.52) | DDB1CRBNNAMPTMAPK1GLS | |
| SCHEMBL31336003 | 0.77 | ABHD6 (0.47) | DDB1CRBNNAMPTMAPK1SMN1; SMN2 | |
| SCHEMBL31335976 | 0.77 | NAMPT (0.54) | DDB1CRBNNAMPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |