Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30303107 | 0.95 | HDAC6 (0.67) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL1049248 | 0.95 | HDAC6 (0.67) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL7740301 | 0.93 | HDAC6 (0.69) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL5493077 | 0.93 | HDAC6 (0.69) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL31336237 | 0.89 | KEAP1 (0.63) | HDAC6DRD2DRD1TAAR1OPRK1 | |
| SCHEMBL65250 | 0.89 | KEAP1 (0.63) | HDAC6DRD2DRD1TAAR1OPRK1 | |
| SCHEMBL29563859 | 0.89 | KEAP1 (0.63) | HDAC6DRD2DRD1TAAR1OPRK1 | |
| SCHEMBL25342051 | 0.88 | HDAC3 (0.76) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| Stearic Acid SCHEMBL28392303 | 0.86 | HDAC6 (0.61) | HDAC6MAPTRXFP1DRD2MGLL | |
| SCHEMBL934635 | 0.85 | HDAC6 (0.59) | HDAC6HDAC3MAPK1ADRA1AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819842-B | Hindered phenol-containing color-resistant antioxidant composition for polymer | 中化泉州石化有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-115819842-A | Coloring-resistant antioxidant composition containing hindered phenol for polymer | 中化泉州石化有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-1260265-C | Polyhydroxy alkanoate and process for producing them with microbe | CANON KK (JP) | 2006-06-21 | — | — | CN | claimed |
| CN-1322768-A | Polyhydroxy alkanoate and process for producing them with microbe | CANON KK (JP) | 2001-11-21 | — | — | CN | claimed |
| US-12435067-B2 | Truncated itraconazole analogues and methods of use thereof | UNIVERSITY OF CONNECTICUT (US) | 2025-10-07 | — | — | US | disclosed |
| CN-115819842-B | Hindered phenol-containing color-resistant antioxidant composition for polymer | 中化泉州石化有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-114606580-B | Nanofiber structure and synthesis method and application thereof | 内布拉斯加大学董事会 | 2024-03-05 | — | — | CN | disclosed |
| CN-115819842-A | Coloring-resistant antioxidant composition containing hindered phenol for polymer | 中化泉州石化有限公司 | 2023-03-21 | — | — | CN | disclosed |
| US-20220324849-A1 | TRUNCATED ITRACONAZOLE ANALOGUES AND METHODS OF USE THEREOF | UNIVERSITY OF CONNECTICUT | 2022-10-13 | — | — | US | disclosed |
| CN-113166087-A | Shielding agent and application thereof | 恩多塞特公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2021030174-A1 | TRUNCATED ITRACONAZOLE ANALOGUES AND METHODS OF USE THEREOF | UNIVERSITY OF CONNECTICUT (US) | 2021-02-18 | — | — | WO | disclosed |
| EP-2205548-A1 | SUBSTITUTED BIPHENYL GPR40 MODULATORS | Amgen, Inc (US) | 2010-07-14 | — | — | EP | disclosed |
| US-6521429-B2 | Using culture media and yeast extracts | CANON KABUSHIKI KAISHA (JP) | 2003-02-18 | — | — | US | disclosed |
| CN-1322768-A | Polyhydroxy alkanoate and process for producing them with microbe | CANON KK (JP) | 2001-11-21 | — | — | CN | disclosed |
| US-20010029039-A1 | Polyhydroxyalkanoates and method of producing them by utilizing mircroorganisms | CANON KABUSHIKI KAISHA (JP) | 2001-10-11 | — | — | US | disclosed |
| EP-1118629-A2 | Polyhydroxyalkanoates and method of producing them by utilizing microorganisms | CANON KABUSHIKI KAISHA (JP) | 2001-07-25 | — | — | EP | disclosed |
| CN-1271363-A | 3' -N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity | ABBOTT LAB (US) | 2000-10-25 | — | — | CN | disclosed |
| EP-0381936-B1 | An electrolyte for use in electrolytic capacitors | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1995-11-29 | — | — | EP | disclosed |
| US-5055974-A | Quaternary ammonium salt of boric acid complex | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0381936-A1 | An electrolyte for use in electrolytic capacitors | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435067-B2 | Truncated itraconazole analogues and methods of use thereof | GLI1, SHH, SMO | HDAC6 401/4885HDAC3 629/4885MAPK1 1495/4885 |
| US-20220324849-A1 | TRUNCATED ITRACONAZOLE ANALOGUES AND METHODS OF USE THEREOF | GLI1, SHH, SMO | HDAC6 401/4885HDAC3 629/4885MAPK1 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.