SCHEMBL3133642

SCHEMBL3133642

NNc1cc[nH]c(=O)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3571371 0.83 DYRK1A (0.35)
SCHEMBL667243 0.78 JAK2 (0.33)
SCHEMBL7876670 0.77
SCHEMBL11894063 0.77
SCHEMBL27952254 0.77 NCF1 (0.39)
SCHEMBL8944768 0.77
SCHEMBL5985571 0.77
SCHEMBL19692379 0.77
N4-Hydroxycytosine SCHEMBL48396 0.77
SCHEMBL4492969 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4056711-B1 METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES SOMALOGIC OPERATING CO INC (US) 2025-09-03 EP claimed
EP-2172566-B2 Method for generating aptamers with improved off-rates SOMALOGIC INC (US) 2022-05-18 EP claimed
EP-4638779-A1 STERILISED APPARATUS FOR CAPTURING NUCLEIC ACIDS FROM BODY FLUIDS Biocaptiva Limited (GB) 2025-10-29 EP disclosed
CN-118974277-A Nucleic acid amplification with higher exponential radix than radix 2 using high and low Tm primers 赛沛公司 2024-11-15 CN disclosed
WO-2024134208-A1 STERILISED APPARATUS FOR CAPTURING NUCLEIC ACIDS FROM BODY FLUIDS BIOCAPTIVA LIMITED (GB) 2024-06-27 WO disclosed
US-20240165267-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF ARES CAPITAL CORPORATION, AS AGENT 2024-05-23 US disclosed
CN-117982528-A Application of schisandra chinensis polysaccharide in preparation of medicines for relieving DSS-induced ulcerative colitis of mice 江苏农牧科技职业学院 2024-05-07 CN disclosed
US-11976309-B2 Fusion proteins and methods for site-directed genome editing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-05-07 US disclosed
CN-117731769-A Nucleic acid vaccine for Varicella Zoster Virus (VZV) 摩登纳特斯有限公司 2024-03-22 CN disclosed
CN-117586413-A Heteromultimeric proteins and methods of making the same 三生国健药业(上海)股份有限公司 2024-02-23 CN disclosed
CN-114667297-B Antibody fusion protein, preparation method thereof and application thereof in resisting tumor 三生国健药业(上海)股份有限公司 2024-02-06 CN disclosed
EP-1784188-A2 FUSED TRIAZOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES Merck & Co., Inc. (US) 2007-05-16 EP disclosed
US-20070037771-A1 Reacting 2-Anhydro-3,5-di-O-(p-toluoyl)-2-C-methyl- alpha -D-ribofuranose with nucleophile such as cytosine, uracil, thymine, hypoxanthine, adenine, guanine, 7-deazaguanine, 7-deazaadenine, 7-deaza-2,6-diaminopurine, and 7-deazahypoxanthine, removing hydroxyl protecting groups MERCK SHARP & DOHME CORP. 2007-02-15 US disclosed
WO-2006070004-A1 COMPOUNDS USEFUL IN THE TREATMENT OF HIV MEDIVIR AB (SE) 2006-07-06 WO disclosed
WO-2006023750-A2 FUSED TRIAZOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES MERCK & CO., INC. (US) 2006-03-02 WO disclosed
EP-1594882-A1 PROCESS FOR PREPARING BRANCHED RIBONUCLEOSIDES FROM 1, 2-ANHYDRORIBOFURANOSE INTERMEDIATES Merck & Co., Inc. (US) 2005-11-16 EP disclosed
US-20050158770-A1 Microwave mediated synthesis of nucleic acid probes VENTANA MEDICAL SYSTEMS, INC. (US) 2005-07-21 US disclosed
WO-2005064018-A2 MICROWAVE MEDIATED SYNTHESIS OF NUCLEIC ACID PROBES VENTANA MEDICAL SYSTEMS, INC. (US) 2005-07-14 WO disclosed
WO-2004072090-A1 PROCESS FOR PREPARING BRANCHED RIBONUCLEOSIDES FROM 1, 2-ANHYDRORIBOFURANOSE INTERMEDIATES MERCK & CO. INC. (US) 2004-08-26 WO disclosed
EP-0209996-A2 Nucleic acid probes comprising N4 -(substituted amino)cytidines SISKA DIAGNOSTICS,INC. (US) 1987-01-28 EP disclosed