SCHEMBL3571371

SCHEMBL3571371

NNNc1cc[nH]c(=O)n1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.35
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3133642 0.83
SCHEMBL28619339 0.79 DYRK1A (0.32) DYRK1AADORA2AADORA1
SCHEMBL28034702 0.77 ALDH1A1 (0.51)
SCHEMBL19692379 0.74
SCHEMBL5985571 0.74
SCHEMBL7876670 0.74
SCHEMBL8944768 0.74
N4-Hydroxycytosine SCHEMBL48396 0.74
SCHEMBL11894063 0.74
SCHEMBL27952254 0.74 NCF1 (0.39) DYRK1AADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE46171-E1 Functional biopolymer modification reagents and uses thereof SOLULINK, INCORPORATED (US) 2016-10-04 US disclosed
US-7732628-B2 Such as 4-[8-(2-cyanoethyl-N,N-diisopropylphosphoramidyloxy)-2-aza-1-oxooct-1-yl]benzaldehyde, 4-[8-(2-cyanoethyl-N,N-diisopropylphosphoramidyloxy)-2-aza-1-oxooct-1-yl]acetophenone; for incorporation into oligonucleotides during immobilization and conjugation of biopolymers in solid phase synthesis SOLULINK INCORPORATED (US) 2010-06-08 US disclosed
US-7102024-B1 Functional biopolymer modification reagents and uses thereof AUDAX PRIVATE DEBT LLC, AS AGENT 2006-09-05 US disclosed
US-20050203289-A1 Functional biopolymer modification reagents and uses thereof AUDAX PRIVATE DEBT LLC, AS AGENT 2005-09-15 US disclosed
WO-2002010431-A2 FUNCTIONAL BIOPOLYMER MODIFICATION REAGENTS AND USES THEREOF SCHWARTZ DAVID A (US) 2002-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050203289-A1 Functional biopolymer modification reagents and uses thereof OGG1, OGA, HMOX2 DYRK1A 2914/4885ADORA2A 1916/4885ADORA1 2997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.