Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336707 | 0.83 | GPBAR1 (0.38) | GPBAR1SLC22A12GRM5POLBALDH1A1 | |
| SCHEMBL31336623 | 0.77 | MEN1 (0.35) | CNR1CNR2GPR119ALDH1A1MEN1 | |
| SCHEMBL31336798 | 0.76 | GABRA1 (0.40) | CNR1CNR2GRM5PDK2POLB | |
| SCHEMBL31336839 | 0.75 | CYP11B2 (0.36) | CNR1CNR2 | |
| SCHEMBL31336792 | 0.74 | GABRA1 (0.38) | CNR1CNR2GRM5 | |
| SCHEMBL19207114 | 0.74 | HCRTR1 (0.39) | CNR1CNR2GPR119POLBALDH1A1 | |
| SCHEMBL31336886 | 0.71 | POLB (0.40) | CNR1CNR2GPR119POLBALDH1A1 | |
| SCHEMBL31336717 | 0.69 | GABRA5 (0.38) | CNR1CNR2GRM5PDK2ALDH1A1 | |
| SCHEMBL31336773 | 0.68 | HCRTR1 (0.37) | CNR1CNR2 | |
| SCHEMBL31336689 | 0.68 | HCRTR1 (0.37) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |