Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 5/20 | 0.33 |
| ▸ | JMJD6 | Q6NYC1 | 4/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336798 | 0.83 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31336769 | 0.83 | JMJD6 (0.39) | GRM5JMJD6 | |
| SCHEMBL31336623 | 0.80 | MEN1 (0.35) | CNR1CNR2 | |
| SCHEMBL31336886 | 0.78 | POLB (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19207114 | 0.76 | HCRTR1 (0.39) | GABRA1GABRG2GABRB3GABRA5CNR1 | |
| SCHEMBL31336717 | 0.76 | GABRA5 (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31336839 | 0.75 | CYP11B2 (0.36) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31336727 | 0.74 | GPBAR1 (0.37) | CNR1CNR2GRM5 | |
| SCHEMBL31336831 | 0.71 | CCR1 (0.33) | ABL1BCR | |
| SCHEMBL31336689 | 0.71 | HCRTR1 (0.37) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |