Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336880 | 0.80 | PDE2A (0.39) | RXFP1PDE2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL31336740 | 0.77 | POLB (0.50) | POLBRXFP1SMN1; SMN2ALDH1A1TNKS | |
| SCHEMBL31336818 | 0.75 | TGFBR1 (0.37) | RXFP1PDE10ASMN1; SMN2ALDH1A1TNKS | |
| SCHEMBL31336658 | 0.73 | ALDH1A1 (0.39) | RXFP1PDE2APDE10ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31336831 | 0.72 | CCR1 (0.33) | POLBPDE2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL31336886 | 0.72 | POLB (0.40) | POLBRXFP1SMN1; SMN2ALDH1A1TNKS | |
| SCHEMBL31336634 | 0.71 | PDE2A (0.35) | RXFP1PDE2ANPC1 | |
| SCHEMBL29320318 | 0.70 | SMN1; SMN2 (0.39) | RXFP1PDE2APDE10ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15258007 | 0.69 | ALDH1A1 (0.57) | RXFP1SMN1; SMN2ALDH1A1TNKSNPC1 | |
| SCHEMBL3147993 | 0.69 | CA12 (0.50) | RXFP1ALDH1A1TNKSNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |