Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336591 | 0.76 | KDM4C (0.46) | ALDH1A1KDM5AKDM2BKDM4CKDM5B | |
| SCHEMBL31336796 | 0.75 | KDM5A (0.40) | ALDH1A1KDM5AKDM2BKDM4CKDM5B | |
| SCHEMBL31336809 | 0.73 | POLB (0.40) | ALDH1A1CYP2A6RXFP1TNKSPDE2A | |
| SCHEMBL31336818 | 0.73 | TGFBR1 (0.37) | ALDH1A1CYP2A6RXFP1TNKSMEN1 | |
| SCHEMBL8029455 | 0.71 | ALDH1A1 (0.58) | ALDH1A1CYP2A6RXFP1MEN1KMT2A | |
| SCHEMBL15258007 | 0.70 | ALDH1A1 (0.57) | ALDH1A1CYP2A6RXFP1TNKSMEN1 | |
| SCHEMBL3147993 | 0.70 | CA12 (0.50) | ALDH1A1RXFP1TNKSMEN1KMT2A | |
| SCHEMBL30335253 | 0.70 | CA12 (0.50) | ALDH1A1RXFP1TNKSMEN1KMT2A | |
| SCHEMBL29320318 | 0.66 | SMN1; SMN2 (0.39) | ALDH1A1CYP2A6RXFP1TNKSMEN1 | |
| SCHEMBL733531 | 0.66 | TUBB4A (0.51) | ALDH1A1CYP2A6MAPTSMN1; SMN2NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |