Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20661372 | 0.82 | ALDH1A1 (0.49) | POLBALDH1A1CA12CA1CA2 | |
| SCHEMBL14333224 | 0.81 | LMNA (0.55) | POLBALDH1A1BAZ2BBAZ2ACA12 | |
| SCHEMBL12489190 | 0.81 | HTT (0.47) | ALDH1A1BRD4TSHRNOTUM | |
| SCHEMBL77311 | 0.80 | NOTUM (0.59) | POLBALDH1A1BAZ2BBAZ2ACA12 | |
| SCHEMBL14333307 | 0.80 | POLB (0.44) | POLBALDH1A1BAZ2BBAZ2ACA12 | |
| SCHEMBL6300267 | 0.80 | KDM4E (0.50) | POLBALDH1A1BAZ2BBAZ2ACA12 | |
| SCHEMBL14333127 | 0.80 | MAPT (0.47) | POLBALDH1A1BAZ2BBAZ2ACA12 | |
| SCHEMBL4538667 | 0.80 | POLB (0.44) | POLBALDH1A1BAZ2BBAZ2ACA12 | |
| SCHEMBL544803 | 0.80 | PKM (0.47) | POLBALDH1A1BAZ2BBAZ2ACA12 | |
| SCHEMBL924812 | 0.80 | NOTUM (0.45) | POLBALDH1A1BAZ2BBAZ2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025050636-A1 | MACROCYCLIC PYRAZOLOPYRIMIDINE COMPOUND AND USE THEREOF | 浙江养生堂天然药物研究所有限公司 | 2025-03-13 | — | — | WO | disclosed |
| CN-119552171-A | Macrocyclic pyrazolopyrimidine compound and application thereof | 浙江养生堂天然药物研究所有限公司 | 2025-03-04 | — | — | CN | disclosed |