Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276880 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL31337488 | 0.80 | POLB (0.45) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL14333224 | 0.80 | LMNA (0.55) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL24930955 | 0.79 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL544803 | 0.79 | PKM (0.47) | KDM4EALDH1A1GAAPOLBBAZ2B | |
| SCHEMBL4538667 | 0.79 | POLB (0.44) | KDM4EALDH1A1GAAPOLBBAZ2B | |
| SCHEMBL14333127 | 0.79 | MAPT (0.47) | KDM4EALDH1A1MAPTGAAATM | |
| SCHEMBL14333307 | 0.79 | POLB (0.44) | KDM4EALDH1A1MAPTGAAPOLB | |
| SCHEMBL924812 | 0.79 | NOTUM (0.45) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL23214997 | 0.76 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240409527-A1 | INHIBITORS OF ALPHA-5 BETA-1 INTEGRIN AND USES THEREOF | UNIV CALIFORNIA (US) | 2024-12-12 | — | — | US | disclosed |
| WO-2023060039-A1 | INHIBITORS OF ALPHA-5 BETA-1 INTEGRIN AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-04-13 | — | — | WO | disclosed |
| US-6841559-B1 | Pyridinones to treat and prevent bacterial infections | WASHINGTON UNIVERSITY OF ST. LOUIS (US) | 2005-01-11 | — | — | US | disclosed |
| EP-1233967-A4 | PYRIDINONES TO TREAT AND PREVENT BACTERIAL INFECTIONS | UNIV WASHINGTON (US) | 2003-07-09 | — | — | EP | disclosed |
| EP-1233967-A1 | PYRIDINONES TO TREAT AND PREVENT BACTERIAL INFECTIONS | WASHINGTON UNIVERSITY (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001036426-A1 | PYRIDINONES TO TREAT AND PREVENT BACTERIAL INFECTIONS | WASHINGTON UNIVERSITY (US) | 2001-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409527-A1 | INHIBITORS OF ALPHA-5 BETA-1 INTEGRIN AND USES THEREOF | ITGB5, ITGA5, ITGB1 | KDM4E 3248/4885ALDH1A1 282/4885MAPT 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.