SCHEMBL31338679

SCHEMBL31338679

Cc1ccc2c(c1)sc1nc(-c3ccc(C(F)(F)F)cc3)cn12

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.53
MAPT P10636 6/20 0.51
TP53 P04637 2/20 0.51
TSHR P16473 1/20 0.51
RAB9A P51151 1/20 0.51
ATM Q13315 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
THRB P10828 2/20 0.50
APP P05067 2/20 0.50
PARP15 Q460N3 1/20 0.48
PARP14 Q460N5 1/20 0.48
PARP10 Q53GL7 1/20 0.48
TNKS2 Q9H2K2 1/20 0.48
PARP2 Q9UGN5 1/20 0.48
F2RL3 Q96RI0 1/20 0.46
RXFP1 Q9HBX9 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11010888 0.84 LMNA (0.58) LMNAMAPTTP53TSHRRAB9A
SCHEMBL24106082 0.83 LMNA (0.70) LMNAMAPTTP53TSHRRAB9A
SCHEMBL31338693 0.83 LMNA (0.47) LMNAMAPTTP53TSHRRAB9A
SCHEMBL13198307 0.82 TP53 (0.66) LMNAMAPTTP53TSHRRAB9A
SCHEMBL804976 0.82 LMNA (0.48) LMNAMAPTTP53TSHRRAB9A
SCHEMBL31338670 0.82 MET (0.52) LMNAMAPTTP53TSHRRAB9A
SCHEMBL3049440 0.81 LMNA (0.53) LMNAMAPTTP53TSHRRAB9A
SCHEMBL10000316 0.81 LMNA (0.59) LMNAMAPTTP53TSHRRAB9A
SCHEMBL31338712 0.79 FLT3 (0.52) LMNAMAPTTP53THRBAPP
SCHEMBL11366406 0.79 F2RL3 (0.44) LMNAMAPTTP53TSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741401-A1 BENZOTHIAZOIMIDAZOLYL COMPOUND AND USE THEREOF ER Stress Research Institute, Inc. (JP) 2026-05-13 EP disclosed
WO-2025009553-A1 BENZOTHIAZOIMIDAZOLYL COMPOUND AND USE THEREOF 小胞体ストレス研究所株式会社 2025-01-09 WO disclosed