SCHEMBL31338977

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.45

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CAPN1	P07384	8/20	0.45

▸	CTSB	P07858	3/20	0.45

▸	REN	P00797	5/20	0.43

▸	F13A1	P00488	1/20	0.41

▸	TGM2	P21980	1/20	0.41

▸	NTSR2	O95665	2/20	0.41

▸	NTSR1	P30989	2/20	0.41

▸	SORT1	Q99523	1/20	0.41

▸	XIAP	P98170	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30963662	0.84	POLB (0.51)	XIAP
SCHEMBL31500753	0.84	CTRB1 (0.47)	—
SCHEMBL15216177	0.82	POLB (0.48)	CTSBXIAP
SCHEMBL22804000	0.82	POLB (0.48)	CTSBXIAP
SCHEMBL20210374	0.82	POLB (0.48)	CTSBXIAP
SCHEMBL29350646	0.82	POLB (0.48)	CTSBXIAP
SCHEMBL31321048	0.81	REN (0.45)	CTSBRENF13A1TGM2NTSR2
SCHEMBL30963663	0.79	XIAP (0.49)	XIAP
SCHEMBL24579345	0.79	ACE (0.49)	REN
SCHEMBL31338976	0.79	REN (0.40)	RENNTSR2NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-119350469-B	Method for synthesizing CAGRILINTIDE by large fragment SPPS-LPPS mixing method	杭州诺澳生物医药科技有限公司	2025-05-23	—	—	CN	disclosed
CN-119350469-A	Method for synthesizing CAGRILINTIDE by large fragment SPPS-LPPS mixing method	杭州诺澳生物医药科技有限公司	2025-01-24	—	—	CN	disclosed