Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31343010 | 0.88 | KDM4C (0.37) | POLBMEN1KMT2AKDM6BKDM4C | |
| SCHEMBL31343097 | 0.84 | CYP3A4 (0.40) | KDM6BKDM4C | |
| SCHEMBL31342873 | 0.82 | ALDH1A1 (0.42) | POLBALDH1A1TSHRGAAKMT2A | |
| SCHEMBL31342987 | 0.82 | ALDH1A1 (0.42) | POLBALDH1A1TSHRGAAKMT2A | |
| SCHEMBL31343012 | 0.80 | CYP3A4 (0.43) | MEN1KMT2AKDM6BKDM4C | |
| SCHEMBL31342907 | 0.80 | SLC6A2 (0.35) | KDM6BKDM4C | |
| SCHEMBL31343033 | 0.79 | CYP3A4 (0.47) | POLBALDH1A1TSHRGAAKDM4E | |
| Hydrochloric Acid SCHEMBL31342872 | 0.79 | SLC6A2 (0.34) | KDM6BKDM4C | |
| SCHEMBL31342829 | 0.77 | GPR119 (0.43) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL31342993 | 0.77 | CYP3A4 (0.44) | CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |