Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31342987 | 1.00 | ALDH1A1 (0.42) | ALDH1A1POLBLMNAKDM4ECYP3A4 | |
| SCHEMBL31343012 | 0.89 | CYP3A4 (0.43) | CYP3A4KMT2AKDM6BKDM4C | |
| SCHEMBL31343010 | 0.86 | KDM4C (0.37) | POLBLMNAKMT2AKDM6BKDM4C | |
| SCHEMBL31343097 | 0.83 | CYP3A4 (0.40) | CYP3A4KDM6BKDM4C | |
| SCHEMBL31343033 | 0.82 | CYP3A4 (0.47) | ALDH1A1POLBLMNAKDM4ECYP3A4 | |
| SCHEMBL31342856 | 0.82 | POLB (0.40) | ALDH1A1POLBKDM4EGAAHTT | |
| SCHEMBL31342829 | 0.80 | GPR119 (0.43) | ALDH1A1CYP3A4HTTKMT2A | |
| SCHEMBL31342993 | 0.80 | CYP3A4 (0.44) | CYP3A4 | |
| SCHEMBL31343032 | 0.80 | TRPC6 (0.38) | ALDH1A1CYP3A4 | |
| SCHEMBL31342907 | 0.78 | SLC6A2 (0.35) | CYP3A4KDM6BKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |