Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.37 |
| ▸ | KDM6B | O15054 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | TSPO | P30536 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31342856 | 0.88 | POLB (0.40) | KDM4CKDM6BMEN1KMT2APOLB | |
| SCHEMBL31342987 | 0.86 | ALDH1A1 (0.42) | KDM4CKDM6BLMNAKMT2APOLB | |
| SCHEMBL31342873 | 0.86 | ALDH1A1 (0.42) | KDM4CKDM6BLMNAKMT2APOLB | |
| SCHEMBL31343012 | 0.84 | CYP3A4 (0.43) | KDM4CKDM6BMEN1KMT2ATRPC6 | |
| SCHEMBL31343097 | 0.84 | CYP3A4 (0.40) | KDM4CKDM6BTRPC6 | |
| SCHEMBL31342907 | 0.84 | SLC6A2 (0.35) | KDM4CKDM6B | |
| SCHEMBL31343033 | 0.83 | CYP3A4 (0.47) | LMNAPOLBTRPC6 | |
| Hydrochloric Acid SCHEMBL31342872 | 0.83 | SLC6A2 (0.34) | KDM4CKDM6B | |
| SCHEMBL31342829 | 0.81 | GPR119 (0.43) | MEN1KMT2AGPBAR1 | |
| SCHEMBL31342993 | 0.80 | CYP3A4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049495-A1 | TERTIARY PYRIDYL AMINE MODULATORS OF CHOLESTEROL BIOSYNTHESIS AND THEIR USE FOR PROMOTING REMYLINATION | GENENTECH, INC. (US) | 2025-03-06 | — | — | WO | disclosed |