SCHEMBL31344175

SCHEMBL31344175

c1ccc(CCC[Te]c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 2/20 0.45
HTR2A P28223 1/20 0.45
IDO1 P14902 1/20 0.43
HDAC3 O15379 1/20 0.43
MAPK1 P28482 1/20 0.43
ADRA1A P35348 1/20 0.43
HDAC4 P56524 1/20 0.43
SLC6A3 Q01959 1/20 0.43
HDAC1 Q13547 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465768 0.86 ALDH1A1 (0.46) SIGMAR1MAOAMAOBHTR2AIDO1
SCHEMBL9517402 0.77 MAOA (0.48) MAOAMAOBIDO1MAPK1ALDH1A1
SCHEMBL31220247 0.74 HDAC3 (0.50) SIGMAR1MAOAMAOBHTR2AIDO1
SCHEMBL31220173 0.74 MAOA (0.43) SIGMAR1MAOASMN1; SMN2
SCHEMBL31343999 0.74 MAOA (0.39) MAOAALDH1A1HSD17B10
SCHEMBL54347 0.74 HTR2A (0.70) SIGMAR1MAOAMAOBHTR2AIDO1
SCHEMBL451456 0.74 MAOA (0.74) SIGMAR1MAOAMAOBHTR2AIDO1
Bromide SCHEMBL11573837 0.73 MAOA (0.42) SIGMAR1MAOASMN1; SMN2ALDH1A1
SCHEMBL8094527 0.72 SIGMAR1 (0.71) SIGMAR1MAOAMAOBL3MBTL1
SCHEMBL8095284 0.72 SIGMAR1 (0.71) SIGMAR1MAOAMAOBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371669-A Aryl-containing asymmetric poly tellurium oxygen alkane and preparation method and application thereof 清华大学 2025-01-28 CN disclosed