Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 4/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12158623 | 0.85 | NOS2 (0.46) | NOS2NISCHKIF11NPSR1 | |
| SCHEMBL17807494 | 0.83 | NOS2 (0.50) | NOS2 | |
| SCHEMBL31344313 | 0.80 | NOS2 (0.42) | NOS2L3MBTL1KIF11CASP3FBP1 | |
| SCHEMBL12158615 | 0.80 | NOS2 (0.50) | NOS2NISCHCHRM1 | |
| SCHEMBL16865684 | 0.80 | NOS2 (0.50) | NOS2NISCHCHRM1NPSR1 | |
| SCHEMBL17807492 | 0.79 | NOS2 (0.53) | NOS2CHRM1NPSR1 | |
| SCHEMBL3056563 | 0.74 | NOS3 (0.45) | NOS2NISCHKIF11CHRM1NPSR1 | |
| SCHEMBL8214663 | 0.74 | NOS2 (0.55) | NOS2L3MBTL1 | |
| SCHEMBL31344192 | 0.72 | CHRM1 (0.40) | NISCHKIF11CYP11B1CYP11B2CHRM1 | |
| SCHEMBL16866585 | 0.72 | MAPK10 (0.49) | NOS2NISCHCYP11B1CYP11B2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306742-A | Arylpiperidine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2025-01-14 | — | — | CN | disclosed |