Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 4/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18905576 | 0.85 | HTR1D (0.39) | NISCHKIF11NPSR1HSP90AA1NPC1 | |
| SCHEMBL18903799 | 0.80 | MAPK10 (0.40) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL3056563 | 0.73 | NOS3 (0.45) | CHRM1NISCHKIF11NPSR1 | |
| SCHEMBL31344191 | 0.72 | NOS2 (0.46) | CHRM1NISCHKIF11CYP11B1CYP11B2 | |
| SCHEMBL3962248 | 0.70 | KIF11 (0.46) | NISCHKIF11CYP11B1CYP11B2NPC1 | |
| SCHEMBL3961810 | 0.70 | KIF11 (0.46) | NISCHKIF11CYP11B1CYP11B2NPC1 | |
| SCHEMBL3073686 | 0.70 | MAPK10 (0.51) | NISCHCYP11B1CYP11B2 | |
| SCHEMBL3070384 | 0.70 | NISCH (0.38) | CHRM1CHRM5NISCHKIF11CYP11B1 | |
| SCHEMBL3066116 | 0.70 | MAPK10 (0.48) | CHRM5NISCH | |
| SCHEMBL3056436 | 0.69 | ENPP1 (0.37) | CHRM1NISCHKIF11CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306742-A | Arylpiperidine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2025-01-14 | — | — | CN | disclosed |