Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31344191 | 0.80 | NOS2 (0.46) | NOS2CASP3NPSR1KIF11L3MBTL1 | |
| SCHEMBL12158623 | 0.69 | NOS2 (0.46) | NOS2NPSR1KDM4EKIF11PLK4 | |
| SCHEMBL811160 | 0.68 | NPSR1 (0.53) | CASP3KDM1ANPSR1KDM4EMAOB | |
| SCHEMBL29595709 | 0.68 | NPSR1 (0.53) | CASP3KDM1ANPSR1KDM4EMAOB | |
| SCHEMBL20422053 | 0.67 | SYK (0.52) | CASP3NPSR1KDM4EKIF11RAB9A | |
| SCHEMBL17807492 | 0.65 | NOS2 (0.53) | NOS2NPSR1PKMPLK4CHEK1 | |
| SCHEMBL556771 | 0.64 | SMN1; SMN2 (0.47) | CASP3NPSR1KDM4EL3MBTL1RAB9A | |
| SCHEMBL30739117 | 0.64 | SMN1; SMN2 (0.47) | CASP3NPSR1KDM4EL3MBTL1RAB9A | |
| SCHEMBL27344645 | 0.63 | KIF11 (0.63) | CASP3KDM1ANPSR1KDM4EMAOB | |
| SCHEMBL3826940 | 0.63 | SMN1; SMN2 (0.46) | CASP3NPSR1KDM4EL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306742-A | Arylpiperidine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2025-01-14 | — | — | CN | disclosed |