SCHEMBL30817470

C[C@@H](O)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)O

nearest known ligand 0.47

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	KEAP1	Q14145	1/20	0.43

▸	KDM1A	O60341	2/20	0.43

▸	MAOB	P27338	1/20	0.43

▸	KDM5A	P29375	1/20	0.43

▸	KDM1B	Q8NB78	1/20	0.43

▸	IL23R	Q5VWK5	1/20	0.42

▸	RAMP3	O60896	4/20	0.42

▸	CALCR	P30988	4/20	0.42

▸	MC4R	P32245	1/20	0.42

▸	NPY2R	P49146	5/20	0.41

▸	NPY4R	P50391	5/20	0.41

▸	NPY5R	Q15761	5/20	0.41

▸	NPY1R	P25929	3/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29801935	0.88	OPRK1 (0.44)	MC4R
SCHEMBL30909415	0.87	ACE (0.44)	KDM1AMAOBKDM5AKDM1BMC4R
SCHEMBL31344445	0.86	KEAP1 (0.51)	KEAP1RAMP3CALCRNPY2RNPY4R
SCHEMBL29801769	0.86	OPRM1 (0.49)	MC4R
SCHEMBL29679604	0.86	RAMP3 (0.57)	RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL30173901	0.86	ACE (0.44)	KDM1AMAOBKDM5AKDM1BNPY2R
SCHEMBL30443975	0.86	ACE (0.45)	KEAP1KDM1AMAOBKDM5AKDM1B
SCHEMBL9551335	0.86	EPHA2 (0.46)	KDM1AMAOBKDM5AKDM1B
SCHEMBL30327352	0.84	EPHA2 (0.47)	KDM1AMAOBKDM5AKDM1BRAMP3
SCHEMBL30868607	0.83	RAMP3 (0.46)	RAMP3CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11965030-B2	Multispecific binding proteins with mutant fab domains	SANOFI (FR)	2024-04-23	—	—	US	disclosed