Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723992 | 0.83 | KMO (0.50) | ALDH1A1KDM4EMTNR1AMTNR1BPOLB | |
| SCHEMBL31403767 | 0.83 | MTNR1A (0.47) | ALDH1A1KDM4EMTNR1AMTNR1BPOLB | |
| SCHEMBL882971 | 0.83 | MTNR1A (0.47) | ALDH1A1KDM4EMTNR1AMTNR1BPOLB | |
| SCHEMBL1324299 | 0.83 | CYP1A2 (0.45) | ALDH1A1KDM4EMTNR1AMTNR1BKMT2A | |
| SCHEMBL30711661 | 0.83 | ATR (0.39) | ALDH1A1KDM4EMTNR1AMTNR1BKMT2A | |
| SCHEMBL6635914 | 0.82 | KDR (0.44) | ALDH1A1KDM4EMTNR1AMTNR1BKMT2A | |
| SCHEMBL2762628 | 0.81 | KDM4E (0.40) | ALDH1A1KDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL28051846 | 0.81 | NNMT (0.50) | ALDH1A1KDM4EMTNR1AMTNR1BPOLB | |
| SCHEMBL20931377 | 0.81 | P2RX7 (0.52) | ALDH1A1KDM4EMTNR1AMTNR1BKMT2A | |
| SCHEMBL31163801 | 0.80 | TDP1 (0.51) | ALDH1A1KDM4ETDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264959-A1 | SUBSTITUTED PYRAZOLOPYRIDINES AS PHOSPHOINOSIDIDE KINASE (PIK) MODULATORS | RECURSION PHARMACEUTICALS, INC. (US) | 2025-12-26 | — | — | WO | disclosed |
| CN-119350323-B | N-sulfonyl amide nitrogen-containing fused heterocycle compounds targeting p53 mutation and application thereof | 上海宇道生物技术有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-119350323-A | N-sulfonyl amide nitrogen-containing fused heterocycle compounds targeting p53 mutation and application thereof | 上海宇道生物技术有限公司 | 2025-01-24 | — | — | CN | disclosed |