Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31344805 | 0.84 | MAOA (0.36) | LMNAHSD17B10MAPK1KDM4EALDH1A1 | |
| SCHEMBL27403358 | 0.70 | KDM4E (0.40) | MAPTHSD17B10USP2MAPK1KDM4E | |
| SCHEMBL30905538 | 0.70 | KDM4E (0.40) | MAPTHSD17B10USP2MAPK1KDM4E | |
| SCHEMBL31303763 | 0.69 | KDM4E (0.43) | HSD17B10USP2MAPK1KDM4EALDH1A1 | |
| SCHEMBL27402501 | 0.68 | LMNA (0.42) | LMNAMAPTUSP2KDM4EALDH1A1 | |
| SCHEMBL30905579 | 0.68 | LMNA (0.42) | LMNAMAPTUSP2KDM4EALDH1A1 | |
| SCHEMBL31344845 | 0.68 | XDH (0.33) | MAPKAPK2 | |
| SCHEMBL30971219 | 0.67 | KDM4E (0.37) | HSD17B10USP2MAPK1KDM4EALDH1A1 | |
| SCHEMBL25384074 | 0.67 | LMNA (0.44) | LMNAMAPTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL30971156 | 0.66 | ALDH1A1 (0.38) | LMNAMAPTUSP2MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569651-A | Carboxamide derivatives, pharmaceutical compositions containing the same, and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-03-07 | — | — | CN | disclosed |