Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LCK | P06239 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 2/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31346221 | 0.86 | BMI1 (0.47) | SMN1; SMN2LCKLMNARAB9ANPC1 | |
| SCHEMBL31346257 | 0.84 | TNKS (0.53) | LCKRAB9ANPC1KMT2ATP53 | |
| SCHEMBL484248 | 0.73 | ALK (0.54) | SMN1; SMN2LCKHSD17B10LMNAHPGD | |
| SCHEMBL11823273 | 0.70 | ALDH1A1 (0.50) | SMN1; SMN2LMNAHPGDKMT2AMAPT | |
| SCHEMBL4131814 | 0.70 | LCK (0.58) | SMN1; SMN2LCKHSD17B10LMNAHPGD | |
| SCHEMBL4931040 | 0.69 | LCK (1.00) | SMN1; SMN2LCKHSD17B10LMNAHPGD | |
| SCHEMBL11480484 | 0.68 | MAPK8 (0.65) | SMN1; SMN2LCKHSD17B10LMNAHPGD | |
| SCHEMBL31346261 | 0.67 | GAA (0.60) | SMN1; SMN2HSD17B10LMNAHPGDMAPK1 | |
| SCHEMBL18056293 | 0.66 | PTPN1 (0.53) | SMN1; SMN2LMNAHPGDMAPK1KMT2A | |
| SCHEMBL31346262 | 0.66 | KDM4E (0.45) | SMN1; SMN2LMNAHPGDMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423763-B | Regioselective synthesis of imidazo [1,2-a ] pyrimidines | 豪夫迈·罗氏有限公司 | 2025-01-21 | — | — | CN | disclosed |