Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347150 | 0.85 | NUDT1 (0.54) | NUDT1MAPTSMN1; SMN2ELANENPC1 | |
| SCHEMBL30989285 | 0.83 | PDE4B (0.49) | NUDT1MAPTSMN1; SMN2ELANENPC1 | |
| SCHEMBL31347076 | 0.76 | ALDH1A1 (0.49) | NUDT1MAPTSMN1; SMN2ELANEKDM4E | |
| SCHEMBL14921642 | 0.75 | NPC1 (0.45) | NUDT1MAPTSMN1; SMN2ELANENPC1 | |
| SCHEMBL25162487 | 0.73 | KDM4E (0.63) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL7820902 | 0.72 | RAB9A (0.50) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL4794157 | 0.72 | KDM4E (0.61) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL21331457 | 0.71 | ALDH1A1 (0.49) | NUDT1MAPTSMN1; SMN2ELANENPC1 | |
| SCHEMBL26622020 | 0.71 | KDM4E (0.67) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL4894562 | 0.71 | NPC1 (0.60) | MAPTSMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585252-A | Bicyclic heteroaryl containing compounds as IKZF2 degrading agents | 翁科皮亚治疗公司和SK生命科学实验室 | 2025-03-07 | — | — | CN | disclosed |