SCHEMBL3134808

SCHEMBL3134808

Cc1ccc(S(O[Cl+3]([O-])([O-])[O-])(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
GAA P10253 4/20 0.40
CA12 O43570 4/20 0.39
CA9 Q16790 4/20 0.39
CA2 P00918 2/20 0.39
CA1 P00915 1/20 0.39
LMNA P02545 4/20 0.39
ALOX12 P18054 2/20 0.39
ACHE P22303 2/20 0.39
TSHR P16473 1/20 0.39
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
CYP2C19 P33261 1/20 0.37
GFER P55789 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3135940 1.00 HTT (0.42) HTTSMN1; SMN2GAACA12CA9
SCHEMBL108184 0.89 HTR6 (0.36) SMN1; SMN2CA12CA9CA2CA1
SCHEMBL3136884 0.85 KMT2A (0.41) SMN1; SMN2LMNAACHEALDH1A1KDM4E
SCHEMBL3135189 0.81 CA4 (0.46) HTTSMN1; SMN2GAACA12CA9
SCHEMBL3144342 0.81 CA4 (0.46) HTTSMN1; SMN2GAACA12CA9
SCHEMBL3132331 0.80 FFAR4 (0.40) HTTSMN1; SMN2GAALMNAALDH1A1
SCHEMBL3140974 0.80 PKM (0.42) TSHRALDH1A1HPGDMEN1KMT2A
SCHEMBL3132383 0.80 TDP1 (0.43) SMN1; SMN2GAACA12CA9CA2
SCHEMBL3126953 0.80 ESR1 (0.39) HTTGAACA12CA9CA2
SCHEMBL3139597 0.80 PKM (0.42) TSHRALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 HTT 1454/4885SMN1; SMN2 4541/4885GAA 972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.