SCHEMBL3126953

SCHEMBL3126953

[O-][Cl+3]([O-])([O-])OS(c1ccccc1)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.39
ESR2 Q92731 2/20 0.39
LTA4H P09960 1/20 0.39
NR1H2 P55055 1/20 0.39
BAX Q07812 1/20 0.39
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
GLA P06280 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA14 Q9ULX7 1/20 0.39
MMP3 P08254 1/20 0.38
BCL2L1 Q07817 1/20 0.38
LMNA P02545 2/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
UQCRB P14927 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108184 0.89 HTR6 (0.36) CA12CA1CA2CA9CA3
SCHEMBL3136673 0.80 TDP1 (0.43) CA12CA1CA2CA9CA3
SCHEMBL3139597 0.80 PKM (0.42) MEN1KMT2APTGS1PTGS2
SCHEMBL3140974 0.80 PKM (0.42) MEN1KMT2APTGS1PTGS2
SCHEMBL3134808 0.80 HTT (0.42) CA12CA1CA2CA9TDP1
SCHEMBL3135940 0.80 HTT (0.42) CA12CA1CA2CA9TDP1
SCHEMBL3132383 0.80 TDP1 (0.43) CA12CA1CA2CA9CA3
SCHEMBL3135189 0.77 CA4 (0.46) LTA4HCA12CA1CA2CA9
SCHEMBL3132410 0.76 ALDH1A1 (0.45) ESR2MEN1KMT2APOLB
SCHEMBL3136062 0.76 ALDH1A1 (0.44) CA1CA2TDP1UQCRBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 ESR1 4560/4885ESR2 3998/4885LTA4H 1387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.