Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037369 | 0.87 | ABL1 (0.51) | ABL1RIN1GNAI3GNAO1GNAI1 | |
| SCHEMBL21837255 | 0.85 | CHRM1 (0.45) | ABL1RIN1GAASMN1; SMN2LMNA | |
| SCHEMBL10130807 | 0.85 | TGM2 (0.41) | ABL1RIN1TGM2GAAMAPT | |
| SCHEMBL17713778 | 0.84 | GAA (0.42) | ABL1RIN1GAAMAPTSMN1; SMN2 | |
| SCHEMBL28761732 | 0.83 | GAA (0.39) | ABL1RIN1GAAMAPTGNAI3 | |
| SCHEMBL31348819 | 0.81 | GAA (0.38) | ABL1RIN1GAAMAPTGNAI3 | |
| SCHEMBL18701859 | 0.80 | TGM2 (0.39) | ABL1RIN1TGM2GAAMAPT | |
| SCHEMBL10074020 | 0.80 | GNAI3 (0.44) | ABL1RIN1TGM2GNAI3GNAO1 | |
| SCHEMBL4712321 | 0.79 | — | — | |
| SCHEMBL23850627 | 0.77 | FAAH (0.35) | ABL1RIN1GAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591611-A | Deuterated tetracyclic derivative and application thereof | 浙江我武翼方药业有限公司 | 2025-03-11 | — | — | CN | disclosed |