Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18657152 | 0.86 | MAPK1 (0.45) | ALDH1A1MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL30401530 | 0.82 | MAPT (0.42) | ALDH1A1MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL6318644 | 0.76 | TSHR (0.48) | ALDH1A1MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL7575151 | 0.74 | CASP3 (0.40) | ALDH1A1MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL10834444 | 0.74 | CA12 (0.51) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL22398101 | 0.73 | TSHR (0.50) | ALDH1A1MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL14664048 | 0.73 | CASP3 (0.63) | ALDH1A1MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL10452222 | 0.73 | CASP3 (0.47) | ALDH1A1MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL10102348 | 0.73 | CASP3 (0.47) | ALDH1A1MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL7581502 | 0.73 | LOXL2 (0.52) | ALDH1A1MAPTMEN1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119112800-A | Nanoparticle for pancreatic cancer treatment by using enamine N-oxide to trigger transcytosis and crossing matrix barrier, and preparation method and application thereof | 衢州市复大生物医药创新研究院 | 2024-12-13 | — | — | CN | claimed |
| CN-119112800-A | Nanoparticle for pancreatic cancer treatment by using enamine N-oxide to trigger transcytosis and crossing matrix barrier, and preparation method and application thereof | 衢州市复大生物医药创新研究院 | 2024-12-13 | — | — | CN | disclosed |