Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443183 | 0.90 | HSPB1 (0.51) | TSHRCASP3SENP8SENP7SENP6 | |
| SCHEMBL22398101 | 0.85 | TSHR (0.50) | TSHRCASP3SENP8SENP7SENP6 | |
| SCHEMBL10640526 | 0.81 | MAPT (0.49) | TSHRCASP3SENP8SENP7SENP6 | |
| SCHEMBL13520587 | 0.81 | PTPN2 (0.49) | TSHRCASP3SENP8SENP7SENP6 | |
| SCHEMBL14664048 | 0.81 | CASP3 (0.63) | TSHRCASP3SENP8SENP7SENP6 | |
| SCHEMBL11338106 | 0.81 | CASP3 (0.47) | TSHRCASP3SENP8SENP7SENP6 | |
| SCHEMBL10452222 | 0.81 | CASP3 (0.47) | TSHRCASP3SENP8SENP7SENP6 | |
| SCHEMBL10102348 | 0.81 | CASP3 (0.47) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL7581502 | 0.81 | LOXL2 (0.52) | TSHRCASP3SENP8SENP7SENP6 | |
| Hydrochloric Acid SCHEMBL21803710 | 0.79 | BLM (0.52) | TSHRCASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466790-B | Preparation method of alpha-sulfinylated carbonyl compound | 西北师范大学 | 2024-05-28 | — | — | CN | claimed |
| CN-117466790-A | Preparation method of alpha-sulfinylated carbonyl compound | 西北师范大学 | 2024-01-30 | — | — | CN | claimed |
| US-20250188068-A1 | AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-06-12 | — | — | US | disclosed |
| US-20240350678-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVISION IMAGING TECHNOLOGIES GMBH (DE) | 2024-10-24 | — | — | US | disclosed |
| EP-4392080-A1 | SYSTEMS AND METHOD FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVision Imaging Technologies GmbH (DE) | 2024-07-03 | — | — | EP | disclosed |
| CN-117466790-B | Preparation method of alpha-sulfinylated carbonyl compound | 西北师范大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-117466790-A | Preparation method of alpha-sulfinylated carbonyl compound | 西北师范大学 | 2024-01-30 | — | — | CN | disclosed |
| US-20230250093-A1 | AMIDO CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-08-10 | — | — | US | disclosed |
| WO-2023026252-A1 | SYSTEMS AND METHOD FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVISION IMAGING TECHNOLOGIES GMBH (DE) | 2023-03-02 | — | — | WO | disclosed |
| CN-110483429-B | Preparation method of 3, 5-disubstituted-4, 5-dihydroisoxazole | 上海应用技术大学 | 2022-10-14 | — | — | CN | disclosed |
| EP-3150585-A1 | CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES WITH EPITHELIAL SODIUM CHANNEL BLOCKING ACTIVITY | Parion Sciences, Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| US-4973750-A | Preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols | SCHERING CORPORATION (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0200739-B1 | PREPARATION OF (THREO)-1-ARYL-2-ACYLAMIDO-3-FLUORO-1-PROPANOLS | SCHERING CORPORATION (US) | 1989-07-19 | — | — | EP | disclosed |
| US-4677214-A | Intermediates for preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols | SCHERING CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0200739-A1 | PREPARATION OF (THREO)-1-ARYL-2-ACYLAMIDO-3-FLUORO-1-PROPANOLS. | SCHERING CORP (US) | 1986-11-12 | — | — | EP | disclosed |
| US-4582918-A | Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols | SCHERING CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| WO-1986001799-A1 | PREPARATION OF (THREO)-1-ARYL-2-ACYLAMIDO-3-FLUORO-1-PROPANOLS | SCHERING CORPORATION (US) | 1986-03-27 | — | — | WO | disclosed |
| US-4219679-A | HIGH CONVERSION | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-08-26 | — | — | US | disclosed |
| US-4216341-A | Selective hydrogenation of certain nitroaromatic hydroxy substituted acetylenes over a heterogeneous RuS2 catalyst | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-08-05 | — | — | US | disclosed |
| US-4139561-A | RUTHENIUM HYDROGENATION CATALYST | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240350678-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | GLS2, HNMT, FH | TSHR 3363/4885CASP3 4408/4885SENP8 3839/4885 |
| US-20230250093-A1 | AMIDO CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | LPAR1, LPAR2, LPAR3 | TSHR 1015/4885CASP3 4014/4885SENP8 3788/4885 |
| US-20250188068-A1 | AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS | LPAR1, LPAR2, LPAR3 | TSHR 922/4885CASP3 3885/4885SENP8 4180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.