Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31349475 | 1.00 | ABL1 (0.34) | ABL1DRD2 | |
| SCHEMBL31349653 | 1.00 | ABL1 (0.34) | ABL1DRD2 | |
| SCHEMBL31349440 | 0.78 | DRD2 (0.30) | DRD2 | |
| SCHEMBL31349476 | 0.78 | DRD2 (0.30) | DRD2 | |
| SCHEMBL31349608 | 0.77 | ADCY10 (0.31) | DRD2 | |
| SCHEMBL31349508 | 0.77 | — | — | |
| SCHEMBL31349501 | 0.77 | DRD2 (0.31) | DRD2 | |
| SCHEMBL25316830 | 0.76 | ADRA2B (0.33) | DRD2 | |
| SCHEMBL30506752 | 0.76 | ADRA2B (0.33) | DRD2 | |
| SCHEMBL26023096 | 0.76 | ADRA2B (0.33) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743078-A2 | APOL1 INHIBITORS AND METHODS OF USE | Maze Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015104-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |